Italy Road Trip Rome To Florence: The Ultimate 2-Week Itinerary

Let’s explore the best of Italy, a country bursting with history, delicious food, and stunning views. This road trip itinerary from Rome to Florence takes you through the heart of Tuscany while soaking up all the amazing things Italy has to offer along the way. From winding roads with beautiful vineyards to medieval towns that take you back in time. Experience the true meaning of La Dolce Vita and wander through the vibrant streets of Rome with its ancient ruins and enjoy artsy Florence, where masterpieces can be found around every corner. Let’s dive into the heart of the country and let your Italy road trip begin!

Italy Road Trip

Experience the best that Italy has to offer, from tasty food and natural hot springs to buzzing cities and everything in between. Combine the most beautiful stops to create your own perfect trip through the land of pasta, wine and endless evenings. An Italy road trip is the best way to see this amazing country, giving you the ultimate freedom to pick and choose what to see and do. Read more about travel to Italy

Day 1-4 – Explore The Ancient Streets Of Rome On Your Italy Road Trip

Let’s explore Rome, Italy’s capital, where ancient history meets modern charm. Marvel at iconic sights like the Colosseum, the Pantheon and Vatican City, stroll through cobblestone streets, and enjoy delicious food at busy trattorias. Whether you’re exploring the historic ruins of the Palatine or simply savoring a gelato on a sunny afternoon, visiting Rome is an amazing experience. In four days you’ll be able to cover most of the highlights and some hidden gems. Because there’s so much to see and do in Rome, four days is the perfect amount of time to explore. Don’t forget to throw a coin in the Trevi Fountain to guarantee your return to the Eternal City!

How To Get To Rome From The Airport

For most visitors, the best airport to fly into is the Rome Leonardo da Vinci Fiumicino Airport. This is the biggest, best served and best connected airport in Rome, and the perfect start for your road trip. Book your plane tickets here

You can easily reach the city center of Rome by train. This will only take you 30 minutes. Alternatively, you can rent a car from here. Keep in mind that Rome is not a car-friendly city and finding a parking spot can be difficult. This is why we chose to pick up our rental after visiting Rome. I recommend to rent a car in Italy through Sunny Cars with free cancellation and insurance included. Book your rental car here

Where To Stay In Rome?

Rome offers accommodations for every budget, and there is a wide range to choose from. There are, however, a couple of wonderful neighborhoods that stand out. Consider staying in the up and coming but very central Monti neighborhood, or stay near the most impressive sights in the Centro Storico. If you don’t mind staying a little further away from the historical center of Rome, the San Lorenzo neighborhood is a great area to stay in. San Lorenzo also tends to be a bit cheaper, so it’s a great choice if you’re traveling on a low budget.

Here are all your hotel options in Rome

Day 5-6 – Start Of Your Italy Road Trip

Let’s hit the road! Say your last goodbyes to beautiful Rome and dive into the countryside. We’re making an extra stop on this scenic route at Lago Bracciano, a beautiful lake located just an hour drive from Rome. You can walk around in one of the sleepy towns, or take a dip in the beautiful blue water at one of the many beaches that surround the lake. This is also the perfect place to rewind after a couple of days in the city.

Enjoy The Natural Hot Springs In Saturnia

End your travel day with a panoramic sunset view on Terme Di Saturnia and its stunning hillside surroundings. This incredible natural hot spring is a popular and busy spot, so make sure to get up early the next day to visit the natural hot springs by sunrise. Spend the morning here and continue your Italy road trip journey to Val D’Orcia at noon.

Where To Stay In Saturnia

There are many good accommodations around Terme Di Saturnia, but they do tend to sell out quickly. It is advised to book your stay ahead of time. We really enjoyed our stay at Saturnia Country Villas, a small B&B which is run by a very sweet local family. They serve an amazing breakfast using only local produce and you will have a wonderful view over the Tuscan hills from their bed & breakfast.

Here are all your hotel options near Terme Di Saturnia

Day 6-8 – A Scenic Drive Through Val D’Orcia To Montepulciano

Driving from Terme Di Saturnia to Montepulciano right through Val D’Orcia is such a treat! Nestled in the heart of Tuscany, Val d’Orcia is a unique and picturesque region with breathtaking landscapes. It offers the perfect mix of rolling hills, vineyards, medieval villages, and of course, the iconic cypress-lined roads. Whether you’re a nature lover, a photography enthusiast, or a history buff, Val d’Orcia has something for everyone. After exploring Val D’Orcia for the day you can step into the past as you wander through Montepulciano’s narrow, cobblestone streets.

Visit Marvelous Montepulciano On Your Italy Road Trip

Marvel at Montepulciano’s well-preserved Renaissance architecture, like the grand Palazzo Comunale and the elegant Palazzo Tarugi. Wander through its medieval streets and get a taste of their exceptional local wine. The wine that Montepulciano is famous for, pairs perfectly with traditional Tuscan dishes, like the savory Pici pasta or a Fiorentina steak. Don’t forget to try the town’s other local specialty, the ricciarelli, a soft almond cookie that melts on your tongue!

Where To Stay In Montepulciano?

Montepulciano offers a range of options to suit every traveler’s taste and budget. From countryside villas and wine estates to rustic agriturismi and budget-friendly guesthouses and B&B’s. Whichever option you choose, you’re sure to enjoy a memorable stay in this enchanting corner of Tuscany, where amazing views, delicious local wines, and historic charm await around every corner.

Here are all your hotel options in Montepulciano

Day 8 – 10 – Explore Historic Siena

Next on your Italy road trip is the beautiful city of Siena. It’s only a short drive from Montepulciano to Siena, so you will have more than enought time to explore! At the heart of Siena lies the Piazza del Campo, an amazing square that’s surrounded by history. It’s also home to the famous Palio horse race. No visit to Siena would be complete without a visit to its stunning cathedral, the Duomo di Siena. With its incredible marble facades and magnificent artworks. There are even some frescoes by Italian masters to admire!

Where To Stay In Siena?

The historic center of Siena is the best place to base yourself, as all of the main sights and attractions are within walking distance. Sienas historic center is car-less, so you can easily explore it by foot. Siena offers a wide range of accommodation options to suit every taste and budget. If you prefer to stay near the main sights, try to find a hotel or bed & breakfast around Piazza del Campo. No luck? Torre and Aquila are both perfect alternatives that are also very close to the main sights in Siena.

Here are all your hotel options in Siena

Day 10-14 – Discover Florence: The Art Capital Of Your Italy Road Trip

Let’s go to Florence, the last stop on your Italy road trip. Florence feels like a living masterpiece, and the city is filled with treasures. The historic city center is relatively compact, which makes it easy to explore. There is a whole lot to see in Florence, so really take your time exploring the city. Wander through its cobblestone streets, visit palaces, elegant piazzas, and enjoy iconic landmarks at every turn. Don’t miss the magnificent Duomo, the buzzing Ponte Veccchio, and the Uffizi Gallery, which is home to one of the world’s most impressive art collections.

Where To Stay In Florence

When you visit Florence, the best option is to stay inside of the historic city center. The neighborhoods Santa Croce and Santa Maria Novella are perfect for escaping the crowds and noise, but the main sights will still be within a short walking distance. Since there is so much to see in the city, a central location will help you save a lot of time on transport.

Here are all your hotel options in Florence

Enjoy Your Italy Road Trip

And that’s it! You finished your perfect two week Italy road trip itinerary. If you’ve already been to Rome or Florence, you can shorten or skip your stay there and branch out a little. From Florence you can visit the small villages of Cinque Terre or the city of Lucca, or you can visit Naples instead of Rome! There are tons of options to tweak this Italy road trip itinerary to your preferences. Have fun!

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